Abstract
Objective: The present study was aimed at investigating the correlation of MRI characteristics of Cerebral Palsy (CP) pediatric patients with their gestational age, type of CP and Gross Motor Function Classification System (GMFCS).
Methods: 120 cases of children with cerebral palsy admitted to our hospital from May 2015 to May 2016 were selected as study subjects. MRI data were observed and the correlation of MRI characteristics was studied with the gestational age, CP type and GMFCS.
Results: The MRI manifestations were recorded with respect to Periventricular White Matter Injury (PWMI), diffuse brain injury, cerebral dysplasia, focal cerebral vascular accident and normal state. They were noticed to be statistically significant (P <0.05). Among 120 cases of children with CP in the group, there were 30 cases with grade I GMFCS (25%), 44 cases with grade II (36.67%), 15 cases (12.5%) with grade III, 25 cases with grade IV (20.83%) and 6 cases with grade V (5%). The differences between the mild/moderate (grade I-III) GMFCS and severe (grade IV-V) GMFCS in the distribution were statistically significant (P <0.05). Moreover, the MRI abnormal rate of premature infants was significantly higher than the MRI abnormal rate of term infants.
Conclusion: The MRI characteristics of children with cerebral palsy were closely correlated with CP type, GMFCS and gestational age. MRI could be used for the early diagnosis and prognosis of such pediatric patients.
Keywords: Cerebral palsy, MRI, GMFCS, gestational age, brain injury, dysplasia.
Graphical Abstract
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