石墨量子点在肿瘤生物成像中的应用进展

Title:Recent Advances in the Cancer Bioimaging with Graphene Quantum Dots

Volume: 25 Issue: 25

关键词: 石墨烯量子点，光致发光，细胞毒性，生物成像，荧光石墨烯量子。

摘要: Fluorescent graphene quantum dots (GQDs) have attracted increasing interest in cancer bioimaging due to their stable photoluminescence (PL), high stability, low cytotoxicity, and good biocompatibility. In this review, we present the synthesis and chemical modification of GQDs firstly, and then introduce their unique physical, chemical, and biological properties like the absorption, PL, and cytotoxicity of GQDs. Finally and most importantly, the recent applications of GQDs in cancer bioimaging are demonstrated in detail, in which we focus on the biofunctionalization of GQDs for specific cancer cell imaging and real-time molecular imaging in live cells. We expect this work would provide valuable guides on the synthesis and modification of GQDs with adjustable properties for various biomedical applications in the future.

Cite this article as:

Recent Advances in the Cancer Bioimaging with Graphene Quantum Dots, Current Medicinal Chemistry 2018; 25 (25) . https://dx.doi.org/10.2174/0929867324666170223154145