Sumoylation in Lens Differentiation and Pathogenesis

Title:Sumoylation in Lens Differentiation and Pathogenesis

Volume: 16 Issue: 10

Author(s): A.-P. Arrigo, D. W.-C. Li, Y.-Z. Liu, J. Gigantelli, Q. Sun, Y.-F. Liu, Z.-W. Luo, F.-Y. Liu, S. Huang, X.-C. Tang, L. Zhang, J.-W. Xiang, T.-H. Yang, R.-L. Qi, Z.-X. Huang, X.-H. Hu, L. Wang, W.-J. Qing, Y. Xiao, L. Gong and Z.-G. Chen

Affiliation:

Keywords: Lens, sumoylation, differentiation, cataractogenesis, pathogenesis.

Abstract: Sumoylation, a post-translational modification discovered over a decade ago, turns out to be a very important regulatory mechanism mediating multiple cellular processes. Recent studies from our laboratory and others also revealed that it plays a crucial role in regulating both differentiation and pathogenesis of the ocular lens. This review will summarize these progresses.

Cite this article as:

Arrigo A.-P., Li W.-C. D., Liu Y.-Z., Gigantelli J., Sun Q., Liu Y.-F., Luo Z.-W., Liu F.-Y., Huang S., Tang X.-C., Zhang L., Xiang J.-W., Yang T.-H., Qi R.-L., Huang Z.-X., Hu X.-H., Wang L., Qing W.-J., Xiao Y., Gong L. and Chen Z.-G., Sumoylation in Lens Differentiation and Pathogenesis, Current Molecular Medicine 2016; 16 (10) . https://dx.doi.org/10.2174/1566524017666170109123238