Abstract
4-Thiazolidinones are sulphur analogues of oxazolidines. They are heterocyclic ring systems which have been explored for their antimicrobial, anticancer, anti-HCV, antifungal, anticonvulsant, antituberculosis, and other activities. While some earlier reviews on the biological activities of this ring system have been reported, the present review describes more recent synthetic strategies and medicinal aspects of 4-thiazolidinones as anticancer agents reported during the past few years (2010-2016).
Keywords: 4-Thiazolidinone, anticancer activity, cytotoxic, diflunisal, etodolac, flurbiprofen, synthesis.
Graphical Abstract