Combinatorial Synthesis in Micro Reactors

P.      Watts; S.   J.   Haswell

doi:10.2174/1386207043328526

Abstract

This article reviews the current and future applications of micro reactors in the field of combinatorial chemistry and drug discovery. Liquid phase reactions have been used to illustrate the advantages of performing chemical reactions in micro reactors which illustrate that reactions can be performed very rapidly in high yield to enable the preparation of combinatorial libraries of structurally related compounds.

Keywords: micro reactors, combinatorial synthesis, structure related libraries, drug discovery

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Combinatorial Chemistry & High Throughput Screening

Title: Combinatorial Synthesis in Micro Reactors

Volume: 7 Issue: 5

Author(s): P. Watts and S. J. Haswell

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Keywords: micro reactors, combinatorial synthesis, structure related libraries, drug discovery

Abstract: This article reviews the current and future applications of micro reactors in the field of combinatorial chemistry and drug discovery. Liquid phase reactions have been used to illustrate the advantages of performing chemical reactions in micro reactors which illustrate that reactions can be performed very rapidly in high yield to enable the preparation of combinatorial libraries of structurally related compounds.

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Watts P. and Haswell J. S., Combinatorial Synthesis in Micro Reactors, Combinatorial Chemistry & High Throughput Screening 2004; 7 (5) . https://dx.doi.org/10.2174/1386207043328526