Abstract
The Diels-Alder (DA) reaction has been applied to the total synthesis of natural products. It can get good yields because of high stereoselectivity and regioselectivity. Herein, the DA reaction catalyzed by Lewis acids was introduced, and some total syntheses of natural products from 2013 to 2015 using DA reaction were also illustrated and analyzed.
Keywords: Diels-Alder reaction, Total synthesis, Applications.
Graphical Abstract