Abstract
Background: In tissue engineering applications, advanced membrane systems provide useful and adaptable biomimetic microenvironment able to sustain cell viability and functions, enabling the delivery and diffusion of biochemical factors, cell nutrients, and products, and mimicking the natural biological extracellular matrix. Proper cell-material interactions favour cell adhesion and trigger cell growth, migration, proliferation, differentiation and functional activation. The wide availability of biocompatible polymers offers the possibility to develop membranes with tuned morphological, physico-chemical, mechanical and transport properties for targeted tissues.
Objective: In this review, an in-depth examination of how the membrane properties are able to influence and direct the cellular morpho-functional behaviour of specific engineered tissues is discussed. Furthermore, an overview of the advanced membrane systems, in different configuration and composition, for the biofabrication of tissues and organs is reported.Keywords: Polymeric membranes, properties, cell-material interactions, biodegradable membranes, non-degradable membranes, biohybrid systems, tissue engineering.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
26
1