Biomaterials and Fabrication to Optimise Scaffold Properties for Musculoskeletal Tissue Engineering

Title:Biomaterials and Fabrication to Optimise Scaffold Properties for Musculoskeletal Tissue Engineering

Volume: 11 Issue: 7

Author(s): Andrew Wheelton, James Mace, Wasim S. Khan and Sanjay Anand

Affiliation:

Keywords: Biomaterials, bioreactors, fabrication, scaffolds, tissue engineering.

Abstract: Tissue engineering has emerged as a promising scientific field potentially yielding in vitro developed tissue to replace degenerative or injured tissues in vivo, thus avoiding the donor site morbidity associated with reconstructive surgery. Integral to the process is the role of scaffolds and the biomaterials used to form them. This review explores the concept of scaffold based tissue engineering and design considerations. The scaffold needs to have certain mechanical and architectural properties, it needs to be biocompatible and biodegradable, and allow combination with bioactive molecules. We also discuss scaffolding techniques, different biomaterial options and fabrication technologies, and future areas of development.

Cite this article as:

Wheelton Andrew, Mace James, Khan S. Wasim and Anand Sanjay, Biomaterials and Fabrication to Optimise Scaffold Properties for Musculoskeletal Tissue Engineering, Current Stem Cell Research & Therapy 2016; 11 (7) . https://dx.doi.org/10.2174/1574888X11666160614101037