Dibenzylbutyrolactone Lignans – A Review of Their Structural Diversity, Biosynthesis, Occurrence, Identification and Importance

Title:Dibenzylbutyrolactone Lignans – A Review of Their Structural Diversity, Biosynthesis, Occurrence, Identification and Importance

Volume: 17 Issue: 12

Author(s): Anna Solyomváry, Szabolcs Beni and Imre Boldizsar*

Affiliation:

• Department of Plant Anatomy, Eötvös Loránd University, Budapest,Hungary

Keywords: Analysis, arctigenin, biosynthesis, chemotaxonomy, dibenzylbutyrolactone, lignan, biological activity.

Abstract: Objective: Dibenzylbutyrolactone lignans represent a unique group of plant secondary metabolites with increasing significance in medicine. This review summarizes their structural characteristics and classification, as well as the biosynthesis starting in the chloroplast, and their supposed biological activity associated with plant defense mechanisms are also discussed. Over 85 natural dibenzylbutyrolactone lignans known to date and their corresponding plant sources are summarized herein for the first time, highlighting a taxon- and organ-specific accumulation of these compounds.

Cite this article as:

Solyomváry Anna, Beni Szabolcs and Boldizsar Imre*, Dibenzylbutyrolactone Lignans – A Review of Their Structural Diversity, Biosynthesis, Occurrence, Identification and Importance, Mini-Reviews in Medicinal Chemistry 2017; 17 (12) . https://dx.doi.org/10.2174/1389557516666160614005828