Oxazole: A Promising Building Block for the Development of Potent Antitumor Agents

Title:Oxazole: A Promising Building Block for the Development of Potent Antitumor Agents

Volume: 16 Issue: 30

Author(s): Hua Zhou, Jiang-Qun Cheng, Zhi-Sen Wang, Fei-Hu Chen and Xin-Hua Liu

Affiliation:

Keywords: Activity, Annulated oxazole, Anticancer inhibitors, Oxazole, Oxazolidinone, Macrocyclic.

Abstract: Oxazole derivatives are found to have a variety of biological activities. A large number of studies have revealed their outstanding anticancer activities. Here we review four different types of oxazole derivatives with anticancer potential reported over the last ten years. We focus our discussion on their activity, selectivity in different cancer cell lines, mechanisms of action, and their structural evolution.

Cite this article as:

Zhou Hua, Cheng Jiang-Qun, Wang Zhi-Sen, Chen Fei-Hu and Liu Xin-Hua, Oxazole: A Promising Building Block for the Development of Potent Antitumor Agents, Current Topics in Medicinal Chemistry 2016; 16 (30) . https://dx.doi.org/10.2174/1568026616666160414122521