Abstract
Cyclobutanones are highly valuable intermediates in organic synthesis. They demonstrate interesting and rich reactivity in different types of reactions due to their strain energy. Under the lewis acid and transition-metal catalysis, cyclobutanones can serve as useful synthons for the preparation of a variety of bioactive molecules and fused-ring chemicals.
Keywords: Cyclobutanones, C-C bond activation, heterocycles, bioactive molecules.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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