Bladder Cancer Chemopreventive Agents: Current Knowledge and Concepts

Title:Bladder Cancer Chemopreventive Agents: Current Knowledge and Concepts

Volume: 18 Issue: 13

Author(s): N. Rezakahn Khajeh, C. Khoyilar, Y. Wu, K. Spradling, X. Zi and R.F. Youssef*

Affiliation:

• Assistant Clinical Professor, Urology Department, University of California, California, Irvine, CA,United States

Keywords: Bladder cancer, heterogeneous disease, Chemoprevention, DNA, Vitamin D, green tea.

Abstract: Bladder cancer is the most prevalent malignancy of the urinary tract and is associated with significant morbidity and mortality. Preventative efforts to reduce the medical and financial burdens of bladder cancer are highly desirable. However, the utilization of natural and pharmaceutical products for the prevention and treatment of bladder cancer remains largely controversial. Herein, we review the current body of evidence surrounding a number of natural dietary substances and their roles in chemoprevention of bladder cancer. Possible chemopreventative properties of several pharmaceutical agents are also reviewed. Overall, the current body of evidence is insufficient to establish a clear link between these proposed chemopreventive agents and risk of bladder cancer.

Cite this article as:

Khajeh Rezakahn N. , Khoyilar C. , Wu Y. , Spradling K. , Zi X. and Youssef R.F.*, Bladder Cancer Chemopreventive Agents: Current Knowledge and Concepts, Mini-Reviews in Medicinal Chemistry 2018; 18 (13) . https://dx.doi.org/10.2174/1389557516666160315114132