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Reviews on Recent Clinical Trials

Editor-in-Chief

ISSN (Print): 1574-8871
ISSN (Online): 1876-1038

Research Article

QT Prolongation and Anticancer Drugs: Is it a Cardiologist’s Worry? The Oncologist’s Point of View

Author(s): Francesca Aroldi, Tiziana Prochilo, Elena Bonini and Alberto Zaniboni

Volume 11, Issue 3, 2016

Page: [260 - 265] Pages: 6

DOI: 10.2174/1574887111666160226150650

Price: $65

Abstract

Currently, many novel therapies are available for physicians treating cancer; some of them are associated with adverse cardiac events. One of the most worrisome cardiac event is QT prolongation, which is a risk factor for developing the potentially fatal torsade de pointe. Many classes of drugs, both anticancer and concomitant agents, are involved in this issue. We report a review of old and new commonly used agents with torsadogenic potential.

Keywords: Adverse cardiac events, cancer, QT prolongation, through QT study, torsade de point.


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