Vascular effects of flavonoids

Title:Vascular effects of flavonoids

Volume: 23 Issue: 1

Author(s): Bruno Almeida Rezende, Aline Carvalho Pereira, Steyner F. Cortes and Virginia Soares Lemos

Affiliation:

Keywords: Cardiovascular system, flavonoids, mechanism, natural products, signaling pathway, vascular effects, vasorelaxation.

Abstract: Flavonoids are natural plant-derived polyphenolic compounds with various biological properties particularly in the cardiovascular system, including antiatherogenic, antioxidant, vasodilation, antihypertensive, and antiplatelet activities. These biological properties have been evaluated in several experimental and clinical studies. In addition, extensive reviews have discussed the antiatherogenic effect of these polyphenols. However, limited studies have investigated the potential therapeutic vascular effects of these compounds. This review brings together some recent studies, to establish the different signaling pathways involved in the molecular mechanisms that underlie the vasodilation induced by flavonoids.

Cite this article as:

Almeida Rezende Bruno, Pereira Carvalho Aline, Cortes F. Steyner and Lemos Soares Virginia, Vascular effects of flavonoids, Current Medicinal Chemistry 2016; 23 (1) . https://dx.doi.org/10.2174/0929867323666151111143616