Recent Advances in Utilities of Active Iodine Reagents as Organo- Catalysts in Organic Synthesis

Title:Recent Advances in Utilities of Active Iodine Reagents as Organo- Catalysts in Organic Synthesis

Volume: 4 Issue: 1

Author(s): Guo-Lin Gao and Qian Chen

Affiliation:

Keywords: Active iodine reagent, hypervalent iodine, iodoarene, organo-catalyst, organo-iodine reagent, quaternary ammonium iodine, tetrabutylammonium iodide.

Abstract: Since 1990s, the application of organo-iodine reagents as oxidant in organic synthesis went through explosive progress. In early times, most of organo-iodine reagents were used as stoichiometric terminal or co-oxidants in oxidative reactions, which inevitably led a lower atom coefficient of utilization and environmental issues. In this regard, it is very urgent to develop varies of efficient approaches of the catalytic utilization of organo-iodine reagents in organic synthesis. Recently, more and more iodine compounds were used as organo-catalysts for many kinds of reactions, which were revolutionary progress for iodine chemistry, and could also meet the need of green chemistry. In this review, we presented an overview of catalytic utilization of active iodine reagents as organo-catalysts in organic synthesis and also some successful examples for asymmetric catalysis. We focused on the recent synthetic strategies, applications of organo-iodine reagents and its mechanism as organo-catalysts, and finally gave a perspective of future development.

Cite this article as:

Gao Guo-Lin and Chen Qian, Recent Advances in Utilities of Active Iodine Reagents as Organo- Catalysts in Organic Synthesis, Current Organocatalysis 2017; 4 (1) . https://dx.doi.org/10.2174/2213337203666151110203733