Abstract
The Pechmann condensation is the formation of coumarin derivatives from phenols and a carboxylic acids or esters containing a β-carbonyl group under acidic conditions. The reaction has attracted a great deal of attention because of the biological significance of coumarins derivatives. As a result, the synthesis of coumarin and its derivatives have been an attractive goal for the chemist. The present review is focused on brief aspects of the synthesis of coumarin derivatives from phenols and a carboxylic acids or esters containing a β-carbonyl group under acidic conditions using various catalysts.
Keywords: Pechmann condensation, coumarins derivatives, heterogeneous catalyst, ionic liquids, microwave, ultrasound, biological activity.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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