Abstract
The synthesis, chemical properties, transformations, and biological activities of mono- and multi- substituted cyclobutyl- and cyclobutenylphosphonates were broadly discussed in this article review. The synthesis of four-membered ring phosphonates was based either on phosphorylation of already constructed cyclobutyl moiety or on inter- and intramolecular cyclizations of phosphorus containing compounds. Also, emphasis was illustrated on the recent development in this field.
Keywords: Four-membered ring, cyclobutanes, cyclobutenes, phosphonates, phosphorylation, phosphonates biological activities.
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