Abstract
Functionalized benzocycloheptenes are one of the most important classes of bicyclic framework that have been critically investigated in different areas of biological activities. Due to interesting skeleton and activities, synthetic chemists were inspired to synthesize them for better understanding of the basic knowledge associated with these compounds. Thus, this review aims to provide insight approaches for construction and functionalization of benzocycloheptene amines and renders useful details for further progress in the area of synthetic methodology. We believe that functionalized benzocycloheptene amine compounds and their various co-components, highlight the existence of numerous potential leads for the development of novel bioactive agents.
Keywords: Amino alcohol, amino ketone, benzocycloheptene amine, bicyclic amine, heterocyclic, oximino ketone.
Graphical Abstract
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Call for Papers in Thematic Issues
31 December, 2024
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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