Thixotropic and Injectable Nature of Supramolecular Aqueous Gels Derived from N,N'-Dibenzoyl-L-cystine and the Effects of Esterification

Title:Thixotropic and Injectable Nature of Supramolecular Aqueous Gels Derived from N,N'-Dibenzoyl-L-cystine and the Effects of Esterification

Volume: 4 Issue: 1

Author(s): Eva-Maria Schon, Jurgen Bachl and David Díaz Díaz

Affiliation:

Keywords: Esterification, gels, injectability, self-assembly, thixotropy.

Abstract: The thixotropic and injectable properties of physical aqueous gels derived from N,N'-dibenzoyl-L-cystine (1, DBC) and its dimethyl ester (2) at room temperature (RT) are described. The characterization of the materials was carried out by oscillatory rheological measurements, including thixotropy-loop tests, and field emission scanning electron microscopy (FE-SEM). Moreover, the effects of gelator concentration and added DMSO on the gel stability are also discussed. Interestingly, comparative studies revealed, among other effects, that esterification of DBC has a positive effect on both the critical gelation concentration (CGC(₁) = 4.5 mM; CGC(₂) = 2.0 mM) and the gel-to-sol transition temperature of the gels (T_gel(₁) = 65 ºC; T_gel(₂) = 78 ºC), whereas the thixotropic-response was significantly hampered.

Cite this article as:

Schon Eva-Maria, Bachl Jurgen and Díaz Díaz David, Thixotropic and Injectable Nature of Supramolecular Aqueous Gels Derived from N,N'-Dibenzoyl-L-cystine and the Effects of Esterification, Nanoscience & Nanotechnology-Asia 2014; 4 (1) . https://dx.doi.org/10.2174/2210681204666140905222744