Synthesis of Some New Pyrano[2,3-b]quinolines from 2-chloro-3- formylquinolones and Meldrum's Acid

Fatiha      Guenfoud; Raouf      Boulcina; Mohammed      Laabassi; Paul      Mosset

doi:10.2174/1570178611666140829214223

Abstract

A new series of functionalized pyrano[2,3-b]quinolines have been prepared in three steps from first condensation of 3-formyl-2-quinolones with Meldrum’s acid, then the corresponding olefins have been alkylated using methyl magnesium iodide, and finally the target compounds have been obtained in good yields after hydrolysis.

Keywords: 3-formyl-2-quinolones, knoevenagel condensation, meldrum’s acid, pyrano[2, 3-b]quinolines.

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Letters in Organic Chemistry

Title:Synthesis of Some New Pyrano[2,3-b]quinolines from 2-chloro-3- formylquinolones and Meldrum's Acid

Volume: 11 Issue: 10

Author(s): Fatiha Guenfoud, Raouf Boulcina, Mohammed Laabassi and Paul Mosset

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Keywords: 3-formyl-2-quinolones, knoevenagel condensation, meldrum’s acid, pyrano[2, 3-b]quinolines.

Abstract: A new series of functionalized pyrano[2,3-b]quinolines have been prepared in three steps from first condensation of 3-formyl-2-quinolones with Meldrum’s acid, then the corresponding olefins have been alkylated using methyl magnesium iodide, and finally the target compounds have been obtained in good yields after hydrolysis.

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Guenfoud Fatiha, Boulcina Raouf, Laabassi Mohammed and Mosset Paul, Synthesis of Some New Pyrano[2,3-b]quinolines from 2-chloro-3- formylquinolones and Meldrum's Acid, Letters in Organic Chemistry 2014; 11 (10) . https://dx.doi.org/10.2174/1570178611666140829214223

DOI https://dx.doi.org/10.2174/1570178611666140829214223	Print ISSN 1570-1786
Publisher Name Bentham Science Publisher	Online ISSN 1875-6255