Low Antimicrobial Toxicity Ionic Liquids: Solvents for Asymmetric Carbonyl- Ene Reactions of Phenylglyoxal

Title:Low Antimicrobial Toxicity Ionic Liquids: Solvents for Asymmetric Carbonyl- Ene Reactions of Phenylglyoxal

Volume: 1 Issue: 3

Author(s): Rohitkumar G. Gore, Thi-Kim-Thu Truong, Marcel Spulak, Stephen J. Connon and Nicholas Gathergood

Affiliation:

Keywords: Antimicrobial toxicity, asymmetric catalysis, carbonyl-ene reaction, ionic liquids.

Abstract: This work demonstrates that low antimicrobial toxicity C2-substituted imidazolium-based ILs, with either ester or amide groups in the side chain, can successfully replace harmful volatile organic compounds (VOCs) in the asymmetric carbonyl-ene reaction of phenylglyoxal with four alkenes catalysed by {[(R)-BINAP]Pd}(SbF₆)₂. Furthermore, the Pd(II) catalyst immobilised in these ILs was recycled and reused up to 5 times without loss of enantioselectivity, although a decrease in yield was observed.

Cite this article as:

Gore G. Rohitkumar, Truong Thi-Kim-Thu, Spulak Marcel, Connon J. Stephen and Gathergood Nicholas, Low Antimicrobial Toxicity Ionic Liquids: Solvents for Asymmetric Carbonyl- Ene Reactions of Phenylglyoxal, Current Green Chemistry 2014; 1 (3) . https://dx.doi.org/10.2174/2213346101666140421220156

DOI https://dx.doi.org/10.2174/2213346101666140421220156	Print ISSN 2213-3461
Publisher Name Bentham Science Publisher	Online ISSN 2213-347X