Abstract
β-Amino ketones are of increasing interest owing to their utility as important synthetic precursors in the synthesis of bioactive molecules and natural products. As a result numerous syntheses of β-amino ketones have emerged in recent years. Of particular significance are those methods that allow access to stereopure β-amino ketones. This review highlights recent advances in stereoselective syntheses of β-amino ketones and also illustrates the importance of β-amino ketones as useful synthons.
Keywords: β-amino ketones, amino alcohols, conjugate additions, diastereoselectivity, enantioselectivity, Mannich addition.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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