Abstract
Tuberculosis is one of the leading causes of morbidity and mortality worldwide. Current treatment has several challenges, such as multi-drug resistance, extensively drug-resistance and HIV co-infection. Problems related to patients, treatment and health care system also contribute negatively to this panel. This review summarizes the main obstacles causing in the treatment of tuberculosis and discusses several strategies to improve the treatment.
Keywords: Drug interactions, extensively drug-resistance, HIV, multi-drug resistance, treatment improvement, tuberculosis, tuberculosis treatment.
Current Clinical Pharmacology
Title:Tuberculosis: Challenges to Improve the Treatment
Volume: 10 Issue: 3
Author(s): Mariana Moreira Lima, Ariane Trindade, Flávia Carnavalli, Aylime Castanho Bolognesi Melchior, Chung Man Chin and Jean Leandro dos Santos
Affiliation:
Keywords: Drug interactions, extensively drug-resistance, HIV, multi-drug resistance, treatment improvement, tuberculosis, tuberculosis treatment.
Abstract: Tuberculosis is one of the leading causes of morbidity and mortality worldwide. Current treatment has several challenges, such as multi-drug resistance, extensively drug-resistance and HIV co-infection. Problems related to patients, treatment and health care system also contribute negatively to this panel. This review summarizes the main obstacles causing in the treatment of tuberculosis and discusses several strategies to improve the treatment.
Export Options
About this article
Cite this article as:
Lima Moreira Mariana, Trindade Ariane, Carnavalli Flávia, Bolognesi Melchior Castanho Aylime, Chin Man Chung and dos Santos Leandro Jean, Tuberculosis: Challenges to Improve the Treatment, Current Clinical Pharmacology 2015; 10 (3) . https://dx.doi.org/10.2174/1574884708666131229124215
DOI https://dx.doi.org/10.2174/1574884708666131229124215 |
Print ISSN 1574-8847 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3938 |
Related Articles
-
Discovering and Developing New Medicines for Malaria Control and Elimination
Infectious Disorders - Drug Targets Synthesis of spirobiindane based bis-flavanones and bis-chroman-4-ones by Kabbe Reaction
Letters in Organic Chemistry β-Carboline Alkaloids: Biochemical and Pharmacological Functions
Current Medicinal Chemistry Recents Patents for Isolating, Delivering and Tracking Adult Stem Cells in Regenerative Medicine
Recent Patents on Drug Delivery & Formulation A Co-Module Regulated by Therapeutic Drugs in a Molecular Subnetwork of Alzheimer’s Disease Identified on the Basis of Traditional Chinese Medicine and SAMP8 Mice
Current Alzheimer Research Drug Delivery Systems: A Few Examples of Applications, Drug Cargoes, and Administration Routes
Current Pharmaceutical Design Targeting the Human Thioredoxin System by Diverse Strategies to Treat Cancer and Other Pathologies
Recent Patents on DNA & Gene Sequences Bioluminescent Quantitation and Detection of Gene Expression During Infectious Disease
Combinatorial Chemistry & High Throughput Screening The Evolution of Extensively Drug Resistant Tuberculosis (XDR-TB): History, Status and Issues for Global Control
Infectious Disorders - Drug Targets Molecular Modeling Based Synthesis and Evaluation of <i>In vitro</i> Anticancer Activity of Indolyl Chalcones
Current Topics in Medicinal Chemistry Hyperglycaemia and Vitamin D: A Systematic Overview
Current Diabetes Reviews Isocitrate Lyase: A Potential Target for Anti-Tubercular Drugs
Recent Patents on Inflammation & Allergy Drug Discovery Exploring Pyrimidine Pharmacophore as Thymidine Monophosphate Kinase Inhibitors for Antitubercular Activity: A Review
Current Topics in Medicinal Chemistry B-Cells and the Use of Non-Human Primates for Evaluation of HIV Vaccine Candidates
Current HIV Research Women’s Health in Central America: The Complexity of Issues and the Need to Focus on Indigenous Healthcare
Current Women`s Health Reviews Drug-induced Inhibition and Trafficking Disruption of ion Channels: Pathogenesis of QT Abnormalities and Drug-induced Fatal Arrhythmias
Current Cardiology Reviews Antimicrobial Peptides: Mediators of Innate Immunity as Templates for the Development of Novel Anti-Infective and Immune Therapeutics
Current Pharmaceutical Design Immunotoxicity and Immunogenicity of Biopharmaceuticals: Design Concepts and Safety Assessment
Current Drug Safety Cardiovascular and Pulmonary Manifestations of Systemic Lupus Erythematosus
Current Rheumatology Reviews The Neuroprotective Effect of Ginkgo biloba Leaf Extract and its Possible Mechanism
Central Nervous System Agents in Medicinal Chemistry