Abstract
Our research group has published numerous papers over the last three years on the reaction of nitrile oxides and azomethine ylide with unsaturated tricyclic N-substituted dicarboximides selected according to the importance of possible biological activities. These reactions cover full range of mechanistic pathways and timings of bond-forming processes to give five-membered ring closure by 1,3-dipolar cycloaddition.
Keywords: Azomethine ylide, biological active molecules, 1, 3-dipolar cycloaddition, hydrazones, isoxazolines, nitrile oxides, tricyclic imides.