Bis-phenylazoneonicotinoids as Divalent Insecticides: Design, Synthesis and Activity

Title:Bis-phenylazoneonicotinoids as Divalent Insecticides: Design, Synthesis and Activity

Volume: 11 Issue: 2

Author(s): Jingwei Zhang, Xusheng Shao, Zhong Li and Xiaoyong Xu

Affiliation:

Keywords: Divalent, Neonicotinoid, Activity, Insecticide.

Abstract: Divalent ligand provides a special approach for designing bioactive molecules. Aiming at searching for novel insecticidal divalent neonicotinoid insecticides, bis-phenylazoneonicotinoids were designed and synthesized here using nitromethylene analogue of imidacloprid, diazo unit and benzene system as pharmacophore, linker and spacer, respectively. The designed divalent compounds exhibited moderate insecticidal activity against cowpea aphids (Aphis craccivora).

Cite this article as:

Zhang Jingwei, Shao Xusheng, Li Zhong and Xu Xiaoyong, Bis-phenylazoneonicotinoids as Divalent Insecticides: Design, Synthesis and Activity, Letters in Drug Design & Discovery 2014; 11 (2) . https://dx.doi.org/10.2174/15701808113109990049

DOI https://dx.doi.org/10.2174/15701808113109990049	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X