TiO₂ NPs as Catalyst for N-Formylation and N-Acetylation of Amines under Solvent–Free Conditions

Title:TiO₂ NPs as Catalyst for N-Formylation and N-Acetylation of Amines under Solvent–Free Conditions

Volume: 10 Issue: 9

Author(s): Mahmood Tajbakhsh, Rahman, Hosseinzadeh, Heshmatollah, Alinezhad, Parizad, Rezaee and Mahgol Tajbakhsh

Affiliation:

Keywords: TiO₂- nanoparticles, N-formylation, N-acetylation, formamides, acetamides, solvent-free.

Abstract: Anatase phase TiO₂- nanoparticles (TiO2 NPs) used as a heterogeneous and highly efficient catalyst for the synthesis of formamides and acetamides by reacting the structurally diverse amines with formic acid and acetic anhydride or acetic acid, respectively, under solvent-free conditions at room temperature. Chemoselectivity, mild and heterogeneous conditions, clean work-up and high reaction yields make this method practical for organic transformations.

Cite this article as:

Tajbakhsh Mahmood, Hosseinzadeh Rahman,, Heshmatollah , Alinezhad , Parizad , Rezaee and Tajbakhsh Mahgol, TiO₂ NPs as Catalyst for N-Formylation and N-Acetylation of Amines under Solvent–Free Conditions, Letters in Organic Chemistry 2013; 10 (9) . https://dx.doi.org/10.2174/15701786113109990031