Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction

Title:Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction

Volume: 19 Issue: 28

Author(s): Rongrong Jing, Ming Cui, Huimin Wang and Shaoqing Ju

Affiliation:

Keywords: Cell-free DNA, biological characteristics, methodology, myocardial infarction.

Abstract: Much attention has been focused on cell-free DNA (cf-DNA) and its levels in the plasma, serum and body fluids of pregnant women and patients with cancer or autoimmune disease, and those with severe trauma; however, knowledge of its biology and relationship with myocardial infarction (MI) is still at an early stage. This paper introduces general aspects of the nomenclature, structure, function, release mechanisms and methodology of cf-DNA and summarizes the current literature on concentration variation and regulatory mechanisms in MI.

Cite this article as:

Jing Rongrong, Cui Ming, Wang Huimin and Ju Shaoqing, Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction, Current Pharmaceutical Design 2013; 19 (28) . https://dx.doi.org/10.2174/1381612811319280012