Abstract
Pyrazoles are compounds of synthetic origin, and constitute a group of nitrogen heterocyclic compounds that have shown several biological activities. Their transformations into other biologically active molecules have been exploited since the early 1960s. This review describes the work on the environment-friendly synthesis of bioactive pyrazoles. The review covers mainly the data published over the last five years (2007–2012).
Keywords: Pyrazoles, green synthesis, bioactivity.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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