A Very Simple, Highly Efficient and Catalyst-free Procedure for the NFormylation of Amines Using Triethyl orthoformate in Water Under Ultrasound-irradiation

Davood      Habibi; Hesam      Sahebekhtiari; Mahmoud      Nasrollahzadeh; Ahmad      Taghipour

doi:10.2174/1570178611310030012

Abstract

N-Formylation of amines has efficiently been carried out in excellent yields by treatment of amines with triethyl orthoformate in water under ultrasound irradiation. The process is remarkably simple and environmentally benign.

Keywords: Amines, Aqueous medium, Catalyst-free, N-formylation, Triethyl orthoformate, Ultrasound irradiation

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Letters in Organic Chemistry

Title:A Very Simple, Highly Efficient and Catalyst-free Procedure for the NFormylation of Amines Using Triethyl orthoformate in Water Under Ultrasound-irradiation

Volume: 10 Issue: 3

Author(s): Davood Habibi, Hesam Sahebekhtiari, Mahmoud Nasrollahzadeh and Ahmad Taghipour

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Keywords: Amines, Aqueous medium, Catalyst-free, N-formylation, Triethyl orthoformate, Ultrasound irradiation

Abstract: N-Formylation of amines has efficiently been carried out in excellent yields by treatment of amines with triethyl orthoformate in water under ultrasound irradiation. The process is remarkably simple and environmentally benign.

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Habibi Davood, Sahebekhtiari Hesam, Nasrollahzadeh Mahmoud and Taghipour Ahmad, A Very Simple, Highly Efficient and Catalyst-free Procedure for the NFormylation of Amines Using Triethyl orthoformate in Water Under Ultrasound-irradiation, Letters in Organic Chemistry 2013; 10 (3) . https://dx.doi.org/10.2174/1570178611310030012