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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Improvement of the Epoxide Hydrolase Properties for the Enantioselective Hydrolysis of Epoxides

Author(s): Laura F. Solares and Cesar Mateo

Volume 17, Issue 7, 2013

Page: [744 - 755] Pages: 12

DOI: 10.2174/1385272811317070008

Price: $65

Abstract

Epoxide hydrolase (EH) is an interesting tool in different processes of organic chemistry. In this review the different available techniques to improve the properties (activity, stability and selectivity) and to enhance the applicability of this enzyme at a large scale will be studied. In particular, the review focuses on immobilization techniques and different examples are presented using different methodologies.

Keywords: Epoxide hydrolase, improved properties, enzyme immobilization, biocatalysis.


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