Advances in the Chemistry of Mannich Bases of Thiophenes and Furans

Gheorghe      Roman

doi:10.2174/1570193X11310010003

Abstract

The advances in the chemistry of Mannich bases of electron-rich, monocyclic five-membered heterocycles with one heteroatom thiophene and furan are reviewed. The aminomethylation of these heterocycles along with the reactivity and the applications of their Mannich bases are summarized.

Keywords: Aminomethylation, mannich reaction, mannich bases, thiophene, furan, drug design

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Mini-Reviews in Organic Chemistry

Title:Advances in the Chemistry of Mannich Bases of Thiophenes and Furans

Volume: 10 Issue: 1

Author(s): Gheorghe Roman

Affiliation:

Keywords: Aminomethylation, mannich reaction, mannich bases, thiophene, furan, drug design

Abstract: The advances in the chemistry of Mannich bases of electron-rich, monocyclic five-membered heterocycles with one heteroatom thiophene and furan are reviewed. The aminomethylation of these heterocycles along with the reactivity and the applications of their Mannich bases are summarized.

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Roman Gheorghe, Advances in the Chemistry of Mannich Bases of Thiophenes and Furans, Mini-Reviews in Organic Chemistry 2013; 10 (1) . https://dx.doi.org/10.2174/1570193X11310010003