Abstract
An ideal drug must be absolutely inert in normal conditions, providing release of active compounds only in diseased areas. Nanoengineered polymeric capsules have required features. We describe here basic methods for the fabrication of such containers and give some particular examples of their use when the drug release is triggered by the presence of the disease itself or by the soft external action, with no side effects on the adjacent tissues.
Keywords: Ideal drug carrier, Layer-by-Layer electrostatic self-assembly, Polyelectrolyte capsules, Targeted drug delivery, Triggered drug release, Bacteriorhodopsin (BR), UV irradiation of azobenzene, Biocompatibilty, Confocal laser scanning microscopy (CLSM), Nanoengineered Polymeric Capsules
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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