Palladium-Catalyzed Cycloaddition of 1,3-Butadiynes with Water: An Alternative Efficient Catalytic System for Atom-Economic Synthesis of 2,5-Disubstituted Furans

Title:Palladium-Catalyzed Cycloaddition of 1,3-Butadiynes with Water: An Alternative Efficient Catalytic System for Atom-Economic Synthesis of 2,5-Disubstituted Furans

Volume: 10 Issue: 1

Author(s): Qingwei Zheng, Ruimao Hua and Tao Yin

Affiliation:

Keywords: Cycloaddition, 1, 3-butadiynes, furan derivative, palladium, water

Abstract: An efficient Pd(PPh3)4/2,5-norbornadiene-catalyzed cycloaddition of 1,4-disubstituted 1,3-butadiynes with H2O under basic conditions for straightforward and simple synthesis of 2,5-disubstituted furans is described.

Cite this article as:

Zheng Qingwei, Hua Ruimao and Yin Tao, Palladium-Catalyzed Cycloaddition of 1,3-Butadiynes with Water: An Alternative Efficient Catalytic System for Atom-Economic Synthesis of 2,5-Disubstituted Furans, Current Organic Synthesis 2013; 10 (1) . https://dx.doi.org/10.2174/1570179411310010007