Abstract
Chiral 2-imidazolidinones have been exploited with respect to asymmetric alkylation reactions, aldol reactions, Michael addition reactions, etc, and their convenient preparation from many kinds of available materials, greater stability to ring-opening reaction than chiral oxazolidinones and high levels of asymmetric induction make them excellent and show more widely considerable promise as chiral auxiliaries in organic synthesis. In this context, the general construction of chiral 2-imidazolidinones will be presented and the most important applications in the field of organic synthesis will be highlighted.
Keywords: 2-Imidazolidinones, Chiral auxiliaries, Asymmetric synthesis, Asymmetric induction.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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