Abstract
This review provides a survey on the reactions of nitrilimines, generated in situ by dehydrohalgenation of the corresponding hydrazonoyl halides, with heterocyclic enones. These reactions proved useful for synthesis of various spiroheterocycles possessing chiral centers and some biological activities.
Keywords: Heterocycles, Hydrazonoyl halides, Nitrilimines, Spiroheterocycles
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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