Abstract
This account intends to cover recent literature on photoinduced cyclization reactions in water or aqueous media. The reactions covered do not proceed by the assistance of metals, or through electron transfer reactions mediated by metallic species or complexes. Radical cyclization of perfluoroalkyl-substituted compounds is neither the subject of this article, since these examples have been reviewed recently. Instead, photomacrocyclization and photoelectrocyclic ring closure reactions are the aims of this article, as well as the syntheses of lactones and 5-methyleneoxazolidin-4-ones, showing the scope of these reactions carried out in an environmentally-friendly media. These cyclization reactions will be shown to enable the syntheses of important synthetic targets, with relevancy in biochemistry and medicinal chemistry.
Keywords: Photocyclization in aqueous media, Electrocyclic ring closure, Oxazolidinones, Photocyclization of phthalimides, 1-ethylpiperidine, benzopyrrolizidine, trimellitic acid substrates, H2O/Me2CO mixtures, X-ray structures, (silylalkyl)phthalimide, N-alkylphthalimide.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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