22% Co/CeO2-ZrO2-catalyzed Synthesis of 1, 2, 3, 4-tetrahydro-2- pyrimidinones and -thiones

Title:22% Co/CeO2-ZrO2-catalyzed Synthesis of 1, 2, 3, 4-tetrahydro-2- pyrimidinones and -thiones

Volume: 9 Issue: 8

Author(s): Hajar Biklarian, Farahnaz K. Behbahani and Zahra Fakhroueian

Affiliation:

Keywords: 22% Co/CeO2-ZrO2, aldehydes, dihydropyrimidinones, 4-dihydropyrimidin-2, calcium, neuropeptide, thiones, HIV, anti-inflammatory, antihypertensive.

Abstract: Three-component condensation reaction of an aldehyde with β-ketoester and urea or thiourea in acetonitrile to afford the dihydropyrimidinones and thions (DHPMs) in the presence of 22% Co/CeO2-ZrO2 nano fine particle as a novel, reusable and green catalyst is reported. Utilizing of 22% Co/CeO2-ZrO2 nano fine particle catalyst also offers a cleaner process in that it can be reused and will not bring additional pollutants into the “environment” that is agreeable green chemistry point of view.

Cite this article as:

Biklarian Hajar, K. Behbahani Farahnaz and Fakhroueian Zahra, 22% Co/CeO2-ZrO2-catalyzed Synthesis of 1, 2, 3, 4-tetrahydro-2- pyrimidinones and -thiones, Letters in Organic Chemistry 2012; 9 (8) . https://dx.doi.org/10.2174/157017812802850159