Dithiocarbamate complexes as radiopharmaceuticals for medical imaging

Title:Dithiocarbamate complexes as radiopharmaceuticals for medical imaging

Volume: 12 Issue: 12

Author(s): David J. Berry, Rafael Torres Martin de Rosales, Putthiporn Charoenphun and Philip J. Blower

Affiliation:

Keywords: Copper, dithiocarbamate, nuclear medicine, radiopharmaceuticals, rhenium, technetium.

Abstract: Over the past 30 years dithiocarbamate ligands have found application in radiopharmaceutical metal-ligand complexes to image a range of disease states. The vast majority of research and applications, and the widest range of complex structures, have involved radionuclides of technetium and rhenium. Considering the extent of coordination chemistry of dithiocarbamate ligands described elsewhere in this issue, the extent of radiopharmaceutical application with metallic radionuclides is surprisingly narrow. Here we summarise the types of radiopharmaceutical complexes studied and the uses, and potential uses, to which they have been put in nuclear medicine.

Cite this article as:

J. Berry David, Torres Martin de Rosales Rafael, Charoenphun Putthiporn and J. Blower Philip, Dithiocarbamate complexes as radiopharmaceuticals for medical imaging, Mini-Reviews in Medicinal Chemistry 2012; 12 (12) . https://dx.doi.org/10.2174/138955712802762112