Redox Chemistry of Green Tea Polyphenols: Therapeutic Benefits in Neurodegenerative Diseases

Title:Redox Chemistry of Green Tea Polyphenols: Therapeutic Benefits in Neurodegenerative Diseases

Volume: 12 Issue: 5

Author(s): H. M. Hugel and N. Jackson

Affiliation:

Keywords: EGCG, green tea antioxidants, prooxidants, anti-cancer, neuroprotection, Alzheimer’s disease

Abstract: Evidence for the medicinal and health benefits of polyphenols in green tea for the prevention of chronic diseases such as heart disease, various types of cancer and neurodegenerative diseases is advancing. Their in vivo effectiveness and molecular mechanisms are difficult to elucidate and remain a challenging task. We review the redox responsiveness and amyloid protein perturbation biophysical properties of the major green tea polyphenol constituent (-)- epigallocatechin-3-gallate [EGCG].

Cite this article as:

M. Hugel H. and Jackson N., Redox Chemistry of Green Tea Polyphenols: Therapeutic Benefits in Neurodegenerative Diseases, Mini-Reviews in Medicinal Chemistry 2012; 12 (5) . https://dx.doi.org/10.2174/138955712800493906