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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Synthetic Methods Applied to the Detection of Chemical Warfare Nerve Agents

Author(s): Braden C. Giordano and Greg E. Collins

Volume 11, Issue 3, 2007

Page: [255 - 265] Pages: 11

DOI: 10.2174/138527207779940883

Price: $65

Abstract

Recent events as they relate to the war on terror make it abundantly clear that the rapid detection of chemical warfare nerve agents is essential. While the detection of these agents clearly falls into the purview of the analytical chemist, the importance of the organic chemist in the development of new techniques or approaches remains intact. This review serves to introduce the reader to a number of methods for detecting nerve agents with a focus on those techniques which rely on synthetic chemistry to improve overall performance with respect to selectivity, sensitivity and analysis time.

Keywords: polymers, surface acoustic wave (SAW), organophosphate nerve agents, AChE inhibitors, coumarinylphenylmaleimide (CPM)


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