Factors Affecting Sexual Transmission of HIV-1: Current Evidence and Implications for Prevention

Title: Factors Affecting Sexual Transmission of HIV-1: Current Evidence and Implications for Prevention

Volume: 3 Issue: 3

Author(s): Derek J. Chan

Affiliation:

Keywords: HIV-1 transmission, spermicidal microbicides, sexually transmissible infections (STIs)

Abstract: The predominant mode of HIV-1 transmission globally is from sexual practices. The risk of HIV-1 transmission by sexual means is a function of infectivity, susceptibility and mode of transmission (type of sexual practice). In addition, transmission may be significantly increased or decreased by factors relating to the HIV-1 per se, sexual behaviour, other sexually transmissible infections (STIs), antiretroviral therapy (ART), spermicidal microbicides and HIV-1 vaccines, the host immune system, genital anatomy and nutritional deficiencies. Current research into the factors affecting sexual transmission of HIV-1 appears to benefit developed nations more than developing nations because of structured public health systems and the capacity to translate research findings into prevention strategies. A redistribution of global aid funding would do much to alleviate the pandemic in developed countries.

Cite this article as:

Chan J. Derek, Factors Affecting Sexual Transmission of HIV-1: Current Evidence and Implications for Prevention, Current HIV Research 2005; 3 (3) . https://dx.doi.org/10.2174/1570162054368075