Functional RNAs as Tools in Proteomics

Title: Functional RNAs as Tools in Proteomics

Volume: 2 Issue: 2

Author(s): N. K. Vaish and S. Zinnen

Affiliation:

Keywords: rna, proteomics

Abstract: Ribozymes and small interfering RNAs (siRNAs) as well as non-natural RNA molecules, such as aptamers, can be used for detection and modulation of gene function at RNA and protein levels. These technologies provide overlapping and complementary methods to antibody-based protein detection. Functional RNAs offer easy to design and simple tools for understanding the function of genes and their products and have potential as therapeutic agents. We review here the advances made with functional RNAs, and illustrate their promise as tools for both in vitro and in vivo proteomic studies.

Cite this article as:

Vaish K. N. and Zinnen S., Functional RNAs as Tools in Proteomics, Current Proteomics 2005; 2 (2) . https://dx.doi.org/10.2174/1570164054494190