Antioxidants Suppress Th1-Type Immune Response In Vitro

Title: Antioxidants Suppress Th1-Type Immune Response In Vitro

Volume: 1 Issue: 3

Author(s): Katharina Schroecksnadel, Birgit Fischer, Harald Schennach, Guenter Weiss and Dietmar Fuchs

Affiliation:

Keywords: Antioxidants, inflammation, neopterin, indoleamine (2,3)-dioxygenase, interferon-γ

Abstract: Inflammation is a hallmark of various diseases like infections, autoimmune syndromes, cardiovascular and neurodegenerative disorders, and cancer. Thereby, Th1-type cytokine interferon-γ is a central pro-inflammatory mediator. Antioxidant compounds counteract the activation of T-cells and macrophages. This anti-inflammatory activity could be important for the development of immunotolerance and for treatment of above-mentioned disorders.

Cite this article as:

Katharina Schroecksnadel , Birgit Fischer , Harald Schennach , Guenter Weiss and Dietmar Fuchs , Antioxidants Suppress Th1-Type Immune Response In Vitro, Drug Metabolism Letters 2007; 1 (3) . https://dx.doi.org/10.2174/187231207781369816