Abstract
L-lysine was applied to the synthesis of 3-substituted coumarins through the condensation of various salicylaldehyde with reactive methylene compounds in water. In this work, waste minimization, catalyst recovery, simple operation and easier product work-up were achieved.
Keywords: Coumarins, green chemistry, knoevenagel condensation, L-lysine, water, optical brightening agents, fluorescent, laser dyes, ethyl acetoacetate, microwave irradiation
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