Abstract
Three-component condensation of substituted acetophenones, aromatic aldehydes, and ammonium acetate catalyzed by silver(I) nitrate adsorbed on silica gel nanoparticles (AgNO3-nano SiO2) has been accomplished for the synthesis of a series of 2,4,6-triaryl pyridines in good to excellent yields under solvent-free conditions.
Keywords: AgNO3-nano SiO2, 2,4,6-triaryl pyridine, krohnke pyridine, solvent-free, organic, sulfadiazine,, anti-HIV, anti-cancer, antiparasitic, heterocyclic