Use of Physicochemical and Topological Parameters in Estimating Anti-Cancer Activity of Benzothiazole Derivatives

Title: Use of Physicochemical and Topological Parameters in Estimating Anti-Cancer Activity of Benzothiazole Derivatives

Volume: 8 Issue: 9

Author(s): Deepali Gupta, Basheerulla Shaik, Jyoti Singh, Neelu Singh and Vijay K. Agrawal

Affiliation:

Keywords: Anticancer, Benzothiazole derivatives, Cross-validation, Multiple linear regression, QSAR, DRAGON softwares, Topological Parameters, Physicochemical, NCSS software, Balaban, Molar volume, Molar refractivity, Index of Refraction, Surface tension, Polarizabilty

Abstract: Several physicochemical and topological descriptors used for estimating anti-cancer activity of benzothiazole derivatives indicated that the use of physicochemical parameters alone yield most appropriate model for modeling the activity.

Cite this article as:

Gupta Deepali, Shaik Basheerulla, Singh Jyoti, Singh Neelu and K. Agrawal Vijay, Use of Physicochemical and Topological Parameters in Estimating Anti-Cancer Activity of Benzothiazole Derivatives, Letters in Drug Design & Discovery 2011; 8 (9) . https://dx.doi.org/10.2174/157018011797200759

DOI https://dx.doi.org/10.2174/157018011797200759	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X