Synthesis of Tetrahydrobenzimidazo[1,2-b]quinazolin-1(2H)-one and Tetrahydro-1,2,4-triazolo[5,1-b]quinazolin-8(4H)-one Ring Systems Under Solvent-Free Conditions

Title: Synthesis of Tetrahydrobenzimidazo[1,2-b]quinazolin-1(2H)-one and Tetrahydro-1,2,4-triazolo[5,1-b]quinazolin-8(4H)-one Ring Systems Under Solvent-Free Conditions

Volume: 9 Issue: 10

Author(s): Ahmad Shaabani, Elham Farhangi and Abbas Rahmati

Affiliation:

Keywords: 2-Aminobenzimidazole, 2-aminobenzothiazole, 3-amino-1,2,4-triazole, cyclic β-diketone, Biginelli-like reaction, multicomponent reaction

Abstract: Tetraheterocyclic benzimidazo[1,2-a]quinazolin-4(1H)-one and tetrahydro-1,2,4-triazolo[5,1-b]quinazolin- 8(4H)-one were synthesized in relatively high yields by the condensation reaction of an aldehyde and a cyclic β-diketone with 2-aminobenzothiazole, 2-aminobenzimidazole or 3-amino-1,2,4-triazole without using any catalyst under solventfree conditions.

Cite this article as:

Shaabani Ahmad, Farhangi Elham and Rahmati Abbas, Synthesis of Tetrahydrobenzimidazo[1,2-b]quinazolin-1(2H)-one and Tetrahydro-1,2,4-triazolo[5,1-b]quinazolin-8(4H)-one Ring Systems Under Solvent-Free Conditions, Combinatorial Chemistry & High Throughput Screening 2006; 9 (10) . https://dx.doi.org/10.2174/138620706779026060

DOI https://dx.doi.org/10.2174/138620706779026060	Print ISSN 1386-2073
Publisher Name Bentham Science Publisher	Online ISSN 1875-5402