Synthesis and DPPH Radical Scavenging Activity of 5-Arylidene-N,Ndimethylbarbiturates

Title: Synthesis and DPPH Radical Scavenging Activity of 5-Arylidene-N,Ndimethylbarbiturates

Volume: 7 Issue: 3

Author(s): Khalid Mohammed Khan, Momin Khan, Muhammad Ali, Muhammad Taha, Abdul Hameed, Sajjad Ali, Shahnaz Perveen and M. Iqbal Choudhary

Affiliation:

Keywords: DPPH Radical scavengers, N,N-dimethylbarbiturates, N,N-dimethylbarbituric acid, DPPH, scavenging activity, antioxidant, spectroscopic techniques, elemental analysis, Barbituric acid, n-propyl gallate

Abstract: Twenty-four derivatives of N,N-dimethylbarbituric acid 1-24 were screened for their DPPH radical scavenging activity. These compounds showed an excellent antioxidant activity. A structure-activity relationship has been discussed, while all the synthetic compounds were characterized by spectroscopic techniques and elemental analysis.

Cite this article as:

Mohammed Khan Khalid, Khan Momin, Ali Muhammad, Taha Muhammad, Hameed Abdul, Ali Sajjad, Perveen Shahnaz and Iqbal Choudhary M., Synthesis and DPPH Radical Scavenging Activity of 5-Arylidene-N,Ndimethylbarbiturates, Medicinal Chemistry 2011; 7 (3) . https://dx.doi.org/10.2174/157340611795564231