Black Light Induced Radical Cyclization Approach to Cyclonucleosides: An Independent Approach

Title: Black Light Induced Radical Cyclization Approach to Cyclonucleosides: An Independent Approach

Volume: 8 Issue: 5

Author(s): Victoria T. Perchyonok

Affiliation:

Keywords: Cyclo-nucleosides, black light, aqueous media, free radical reactions, dihydrothymidine, deoxyribose, chromatographic, diastereoisomers, oligonucleotides, cyclopyrimidine

Abstract: The paper highlights an efficient methodology based on consecutive radical reaction for the preparation of cyclonucleoside derivatives. The reactions were performed in organic and aqueous media, using common and efficient free radical hydrogen donors in the range of innovative and conventional initiation conditions to afford good to excellent yields of corresponding cyclonucleosides. The mechanistic aspects of the transformations are also addressed.

Cite this article as:

T. Perchyonok Victoria, Black Light Induced Radical Cyclization Approach to Cyclonucleosides: An Independent Approach, Letters in Organic Chemistry 2011; 8 (5) . https://dx.doi.org/10.2174/157017811795685108