Coupling Reaction of Acid Chlorides with Terminal Alkynes Catalyzed by Diatomite-Supported Palladium(II) Salophen Complex

Title: Coupling Reaction of Acid Chlorides with Terminal Alkynes Catalyzed by Diatomite-Supported Palladium(II) Salophen Complex

Volume: 8 Issue: 5

Author(s): Mohammad Bakherad, Ali Keivanloo, Bahram Bahramian, Zahra Kalantar and Faezeh N. Ashrafi

Affiliation:

Keywords: Copper-free, sonogashira reaction, supported catalyst, acid chlorides, alkynyl, acylation, polystyrene-supported, bidentate, phosphine, palladium

Abstract: A highly-efficient method for the copper- and solvent-free coupling reaction of acid chlorides and terminal alkynes catalyzed by diatomite-supported palladium(II) salophen complex is described. Acid chlorides are easily coupled with terminal alkynes, giving good to high yields in the presence of a low catalyst loading (1 mol% Pd) in DIEA at room temperature under aerobic conditions. After centrifugation, the supported catalyst is able to be recycled and reused for several times with only a slight decrease in activity.

Cite this article as:

Bakherad Mohammad, Keivanloo Ali, Bahramian Bahram, Kalantar Zahra and N. Ashrafi Faezeh, Coupling Reaction of Acid Chlorides with Terminal Alkynes Catalyzed by Diatomite-Supported Palladium(II) Salophen Complex, Letters in Organic Chemistry 2011; 8 (5) . https://dx.doi.org/10.2174/157017811795685117